The following reactions have been reported, a causal relationship to the administration of danazol has neither been confirmed nor refuted; allergic urticaria, pruritus and rarely, nasal congestion; cns effects headache, nervousness and emotional lability, dizziness and fainting, depression, fatigue, sleep disorders, tremor, paresthesias, weakness, visual disturbances, and rarely, benign intracranial hypertension, anxiety, changes in appetite, chills, and rarely convulsions, guillain-barre syndrome; gastrointestinal gastroenteritis, nausea, vomiting, constipation, and rarely, pancreatitis and splenic peliosis; musculoskeletal muscle cramps or spasms, or pains, joint pain, joint lockup, joint swelling, pain in back, neck, or extremities, and rarely, carpal tunnel syndrome which may be secondary to fluid retention; genitourinary hematuria, prolonged posttherapy amenorrhea; hematologic an increase in red cell and platelet count.
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Breast tissue is also under the control of sex hormones, and danazol can be used to relieve severe breast pain and tenderness in benign fibrocystic breast disease.
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these drugs include diuretics, for example, hydrochlorothiazide microzide, and many combinations with other drugs , loop diuretics for example, furosemide lasix , corticosteroids such as prednisone and methylprednisolone medrol , phenytoin dilantin , colesevelam welchol , danazol and somatropin genotropin .