Researchers at the university of texas southwestern medical center at dallas ut southwestern have completed a study showing that topamax can increase the propensity for calcium phosphate kidney stones.
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in the 6-month migraine prophylaxis controlled trials, which used a slower titration regimen 25 mg day weekly increments , the proportion of patients who experienced one or more cognitive-related adverse reactions was 19 for topamax 50 mg day, 22 for 100 mg day the recommended dose , 28 for 200 mg day, and 10 for placebo.
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of the 1,135 patients exposed to topamax in the adult placebo-controlled studies, 25 of topamax -treated patients discontinued due to adverse reactions, compared to 10 of the 445 placebo-treated patients.
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